For all PRACTICAL purposes the D-50 is the first VA synth.
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It can sound very artificial analog in a way that cannot be replicated by any other synths, including its own clones like the Boutique D-05, Roland Cloud, V-synth D-50 card add-on or the VST version.
Only the original D-50/550 can sound like this.

I sell many of the patches you hear in this video. Contact me directly if you're interested.