In the year 1492 DR, over 120 years after the events of Baldur's Gate II: Shadows of Amn and months after the events of Baldur's Gate: Descent into Avernus, the forces of darkness are rising again. We have been taken captive by the mind flayers, who have launched an invasion of Faerûn. They have implanted us with some kind of parasite, as well as a host of other creatures, with illithid tadpoles, parasites capable of enthralling and transforming them into other mind flayers; however, before the mind flayers can transform their victims, the nautiloid flying ship upon which they are all aboard comes under attack from githyanki warriors and their red dragons, and flees through multiple realms, including Avernus, the first of the Nine Hells. We are freed during the fighting, where we fight through the ship to hopefully find a way to bring it back to Faerûn. Will we make it back home, or will we be forever stuck with Mind flayers and demons? Once back, will we be able to find a way to remove these parasites from our head? Can we even get back to being normal, or will we be doomed to become new Mind flayers?