It's kind of difficult to translate '抜けてる' in this context into English... I chose the direct translation and said 'he is missing something'. After a little more research, another way to put it would be: missing a page in a book. Him being the book and the nonstandard answer being a result of missing a page.

Stream:
にじフェスありがとうございました！振り返り雑談！【 神田笑一/にじさんじ 】
https://www.youtube.com/live/pdTks0Is...

VTubers mentioned:
@KandaShoichi
@MurakumoKagetsu

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