A supposedly professional painter has some trouble capturing the true beauty of a mans wife leading to disappointment all around and one bloody nose.

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Season5 Episode 3 "Adverse Events"
A painter's undiagnosed illness begins to affect his work, but he is unable to see his art is suddenly grotesque. He is brought to Princeton-Plainsboro Hospital, though he claims that he is getting better. House grows suspicious when he learns that the painter was fearful of a test involving the injection of a dye. It is later revealed that he is on three separate drug trials, which he was hiding from his girlfriend. Meanwhile, House continues to use Lucas to obtain information about his team and to learn more about Cuddy's personal life

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