Chad provides a comprehensive lesson on the Ring Opening of Epoxides. This can be done under two conditions with varying regiospecificity, and ring opening in the presence of a strong nucleophile is covered first (sometimes called base catalyzed ring opening of epoxides), while acid catalyzed ring opening of epoxides is covered second. Chad concludes the lesson by providing an example of Grignard addition to an epoxide.

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00:00 Lesson Introduction
00:26 Ring Opening of Epoxides with Strong Nucleophiles
3:17 Acid-Catalyzed Ring Opening of Epoxides
8:39 Grignard Addition to Epoxides