The CDC’s Advisory Committee on Immunization Practices (ACIP) recommended a new monoclonal antibody shot that can protect babies from RSV. The AMA’s ACIP liaison, Sandra Fryhofer, MD, joins to discuss the recommendation and details of the shot, including who should get it, how often and what the side effects are. American Medical Association CXO Todd Unger hosts.

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00:00 AMA Update for August 10, 2023
00:42 RSV monoclonal antibody for babies approved by FDA (AstraZeneca, Sanofi)
01:27 Is RSV the leading cause of hospitalization in infants?
01:30 RSV symptoms in babies
01:47 Is RSV fatal in infants?
01:54 RSV hospitalization rates: What percentage of babies get RSV?
02:48 RSV monoclonal antibodies for infants and neonates
03:06 RSV seasons
03:20 RSV injection for infants approved by FDA (toddlers, children up to 24 months)
03:35 Nirsevimab recommended for babies under 8 months
03:51 RSV prevention for infants 8-19 months old
04:21 Protective dose recommended for babies' second RSV season
04:42 RSV prevention shot for babies with cystic fibrosis and severe lung disease
04:55 RSV in immunocompromised and Indigenous American children (American Indian, Alaska Native)
05:29 FDA approved Beyfortus (clinical trials, study data)
05:56 Efficacy of Beyfortus (nirsevimab efficacy)
06:30 RSV shot side effects (adverse reactions, #VAERS)
07:19 RSV treatment cost
07:47 RSV shot doses for babies
08:50 RSV immunizations: RSV vaccine vs monoclonal antibodies (induced vs passive immunity)
09:56 RSV in adults
10:07 FDA approved RSV vaccines for adults (ACIP Shared Clinical Decision-Making Recommendation)
10:30 Risk of severe RSV in older adults (COPD, asthma, heart disease, diabetes, etc.)
10:58 RSV vaccines during pregnancy
11:14 Palivizumab: Synagis cost, dose, effectiveness
11:46 Beyfortus price: Is nirsevimab covered by health insurance or ACA?
12:26 #CDC recommended nirsevimab for Vaccines for Children (VFC program)
12:51 Is nirsevimab effective against RSV? (Respiratory Syncytial Virus hospitalizations, lower respiratory tract infections)

Visit the AMA Update video page for more videos in this series: https://www.ama-assn.org/ama-update-v....

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