Las #alergias son una reacción del sistema inmunitario en respuesta a los #alergenos alimentarios o ambientales, en ocasiones es por una predisposición genética y es el resultado desafortunado de la evolución de la respuesta inmunitaria con IgE en contra de #parasitos metazoarios. Conoce aquí lo que está detrás de esta respuesta inmunitaria.

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Artículos consultados:

Akdis, C. A., Akdis, M., Boyd, S. D., Sampath, V., Galli, S. J., & Nadeau, K. C. (2023). Allergy: Mechanistic insights into new methods of prevention and therapy. Science translational medicine, 15(679), eadd2563. https://doi.org/10.1126/scitranslmed....

Vander Does, A., Labib, A., & Yosipovitch, G. (2022). Update on mosquito bite reaction: Itch and hypersensitivity, pathophysiology, prevention, and treatment. Frontiers in immunology, 13, 1024559. https://doi.org/10.3389/fimmu.2022.10...

Campbell, E., Hesser, L. A., & Nagler, C. R. (2021). B cells and the microbiota: a missing connection in food allergy. Mucosal immunology, 14(1), 4–13. https://doi.org/10.1038/s41385-020-00...

Pacheco, S. E., Guidos-Fogelbach, G., Annesi-Maesano, I., Pawankar, R., D' Amato, G., Latour-Staffeld, P., Urrutia-Pereira, M., Kesic, M. J., Hernandez, M. L., & American Academy of Allergy, Asthma & Immunology Environmental Exposures and Respiratory Health Committee (2021). Climate change and global issues in allergy and immunology. The Journal of allergy and clinical immunology, 148(6), 1366–1377. https://doi.org/10.1016/j.jaci.2021.1...

Pierau, M., Arra, A., & Brunner-Weinzierl, M. C. (2021). Preventing Atopic Diseases During Childhood - Early Exposure Matters. Frontiers in immunology, 12, 617731. https://doi.org/10.3389/fimmu.2021.61...

Alkotob, S. S., Cannedy, C., Harter, K., Movassagh, H., Paudel, B., Prunicki, M., Sampath, V., Schikowski, T., Smith, E., Zhao, Q., Traidl-Hoffmann, C., & Nadeau, K. C. (2020). Advances and novel developments in environmental influences on the development of atopic diseases. Allergy, 75(12), 3077–3086. https://doi.org/10.1111/all.14624

McSorley, H. J., Chayé, M. A. M., & Smits, H. H. (2019). Worms: Pernicious parasites or allies against allergies?. Parasite immunology, 41(6), e12574. https://doi.org/10.1111/pim.12574

Fitzsimmons, C. M., Falcone, F. H., & Dunne, D. W. (2014). Helminth Allergens, Parasite-Specific IgE, and Its Protective Role in Human Immunity. Frontiers in immunology, 5, 61. https://doi.org/10.3389/fimmu.2014.00061

Prokopakis, E., Vardouniotis, A., Kawauchi, H., Scadding, G., Georgalas, C., Hellings, P., Velegrakis, G., & Kalogjera, L. (2013). The pathophysiology of the hygiene hypothesis. International journal of pediatric otorhinolaryngology, 77(7), 1065–1071. https://doi.org/10.1016/j.ijporl.2013...

Fitzsimmons, C. M., & Dunne, D. W. (2009). Survival of the fittest: allergology or parasitology?. Trends in parasitology, 25(10), 447–451. https://doi.org/10.1016/j.pt.2009.07.004

Fallon, P. G., & Mangan, N. E. (2007). Suppression of TH2-type allergic reactions by helminth infection. Nature reviews. Immunology, 7(3), 220–230. https://doi.org/10.1038/nri2039
Kim, Y. K., Cho, S. H., Koh, Y. Y., Son, J. W., Lee, B. J., Min, K. U., & Kim, Y. Y. (1999). Linkage between IgE receptor-mediated histamine releasability from basophils and gene marker of chromosome 11q13. The Journal of allergy and clinical immunology, 104(3 Pt 1), 618–622. https://doi.org/10.1016/s0091-6749(99...

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Libros recomendados:
- Male, D, Stokes Peebles, R, Male, V. (2021). Inmunología. Elsevier.
- Thao, D, Richard A. Harvey, RA. (2021). LIR Inmunología. LWW Wolters Kluwer.
- Abbas, AK, Lichtman, AH, Pillai, S. (2020). Inmunología Básica. Elsevier.
- Punt, J, Strandford, SA, Jones PP, Owen JA. (2020). Kuby. Inmunología. McGrawHill.
- Sompayrac, LM. (2019). How the Immune System Works. Wiley-Blackwell
- Tizard, I. (2019). Inmunología Veterinaria. Elsevier.

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