Transperineal prostate biopsy refers to the insertion of a needle through the perineum (the area between the scrotum and anus) into the prostate to obtain prostatic tissue for testing. This procedure is indicated when you have an elevated prostate specific antigen (PSA), abnormal digital rectal examination or magnetic resonance imaging (MRI) findings. A small amount of prostatic tissue is obtained in order to determine if there are any cells suspicious of prostate cancer.

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