I'm afraid it's been 9 years since TPP released, so this is the perfect time to do a full playthrough with the Infinite Heaven OSP (On-site procurement) mod that makes all missions like the "Subsistence" special repeat-missions where you start the mission with absolutely nothing at all in your inventory.

Let's go over the key factors in terms of restrictions:
The aforementioned weapons and equipment OSP
No Reflex Mode (and obviously no Chicken hat)
No supply drops or any kind of support fire or weather modification from Mother Base
D-Horse is the only buddy I use, to travel long distances faster
The only camo I wear is the standard Olive Drab camouflage
No Prosthetic Arm upgrades whatsoever (however I will be making an exception to this for Ep. 45 "A Quiet Exit" and getting the mobility upgrades for that mission specifically)

It's not all about restrictions however. I use a couple quality-of-life mods as well, namely the "no more timers" mod which lets you develop any upgrades instantly without having to wait a ridiculously long time for them. The other mod I use cuts down on waiting as well - it is part of the "Infinite Heaven" mod and it allows you to skip the painfully boring helicopter rides. Most missions start with Snake already on the ground.
I will also be earning the S rank in every mission (except the repeat missions in Chapter 2 which I will not even do) and completing the "Perfect Stealth, No Kills"-challenge in most of them, as well as the "No Traces"-challenge (which means you can't be spotted nor even touch any enemies) in some.

This Part dissected:
0:00 Intro
5:44 Prologue: Awakening
1:06:16 Ep. 1: Phantom Limbs
1:41:12 Ep. 2: Diamond Dogs
1:56:54 Ep. 3: A Hero's Way
2:09:38 Ep. 4: C2W
2:33:46 Puppy DD Cutscene
2:40:11 Ep. 5: Over The Fence
2:53:59 Ep. 6: Where Do The Bees Sleep?
3:18:10 Meeting Skull Face and the Skulls (1st Boss Battle)
3:31:07 Puppy DD Cutscene 2
3:36:08 Ep. 7: Red Brass
3:46:33 Ep. 11: Cloaked in Silence