Novosibirsk, Russia by Drone Footage Novosibirsk is a city in Siberia, southern Russia, bisected by the Ob River. The Trans-Siberian Railway fueled much of the city's 19th-century growth, symbolized by the Novosibirsk Rail Bridge, which still stands today. In the city center is the 19th-century, Byzantine-style Alexander Nevsky Cathedral, with its golden domes. The expansive Novosibirsk Opera and Ballet Theatre borders Lenin Square.