NTU OpenCourseWare
Course Title: Principles of Epidemiology
Instructor: Chin-Kuo Chang, Institute of Epidemiology and Preventive Medicine
Unit URL: http://ocw.aca.ntu.edu.tw/ntu-ocw/ocw...
License: Unless noted, this work is licensed by Chin-Kuo Chang for the use of NTU OCW ONLY. The copyright belongs to the above mentioned licensor.

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00:00:00 Opening ~ Unit Title
00:00:15 Introduction
00:00:45 Outline
00:03:18 Natural Experiment
00:06:35 Thyromegaly (goiter)
00:07:19 The Strength of Evidence
00:10:53 The Advantages of RCTs
00:12:53 RCT might be the only chance for Nature as an epidemiologist…
00:14:08 Prototype of RCT Design – The most rigorous methodology in Epi
00:17:39 Prototype of RCT Design
00:19:37 Utilizing Run-in Design
00:20:18 Frame of Run-in Design
00:21:15 Factorial Design
00:23:39 Time Series Design – Compare to historical controls
00:24:48 Time Series Design
00:25:29 Cross-Over Design
00:28:16 Selection of Subjects
00:34:51 What are the inclusion and exclusion criteria for? – Representativeness versus Homogeneity
00:35:15 Randomization
00:39:25 Blindness (Masking)
00:43:39 Noncompliance
00:46:25 Sources of Bias in RCT
00:48:50 Dilemma
00:53:11 Ethical Aspects
00:57:18 Copyrights ~ Ending

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